Cannabis Sativa L. - the commercial and healing plant
Hemp (cannabis) was already cultivated as a useful and medicinal plant in China around 8,000 BC and their first use for medicinal purposes about 5000 years ago. Active compounds are found in all cannabis plants, but not always in the same quantity or even in the same composition. There are three major groups of compounds in cannabis. These are cannabinoids, terpenes and flavonoids. In the late 1990s, research into the interplay between cannabinoids and terpenes presented another interesting aspect in this context.
The “entourage effect” was first characterized by Dr. Ben-Shabat in 1998 and has been explained and expanded upon, particularly by Dr. Ethan Russo. Dr. Ethan Russo, M.D., a neurologist who has long been significantly involved with cannabis compounds and their role in the body, published the following study “Taming THC: potential cannabis synergy and phytocannabinoid-terpenoid entourage effects” in 2011.